What Is Automated Particle Analysis?
Micrometry Automator performs automated particle analysis on microscopy images using an advanced OpenCV-based image processing pipeline. It detects individual particles, measures their area, perimeter, equivalent diameter, and circularity in both pixels and calibrated micron units, then computes full D-value statistics including D10, D50, D90, D95, D99, and D100.
- Automated detection pipeline: Grayscale → CLAHE → Gaussian Blur → Otsu Threshold → Morphological Cleanup → Contour Detection
- Watershed segmentation for separating agglomerated particles with configurable separation factor
- Per-particle metrics: area (µm²), perimeter (µm), equivalent diameter (µm), circularity index
- Colored overlay visualization with semi-transparent highlights and particle labels
- Saveable analysis method presets (threshold, min/max area, min/max diameter filters)
Screenshot coming soon
What Are D-Values in Particle Analysis?
D-values (D10, D50, D90, D95, D99, D100) represent the particle diameter at which a given percentage of particles fall below that size in a cumulative distribution. Micrometry Automator automatically computes all D-values along with mean, median, and standard deviation from detected particles — essential for pharmaceutical particle size specifications and quality control.
| Statistic | Description |
|---|---|
| D10 | 10% of particles below this diameter |
| D50 | Median particle diameter (50th percentile) |
| D90 | 90% of particles below this diameter |
| D95 | 95th percentile diameter |
| D99 | 99th percentile diameter |
| D100 | Maximum particle diameter |
| Mean / Median | Average and median equivalent diameter |
| Std Dev | Standard deviation of the size distribution |
Screenshot coming soon
What Is Leaf Vein Analysis in Pharmacognosy?
Leaf vein analysis is a pharmacognosy technique used to authenticate and characterize botanical drug substances by counting vein islets (closed loops formed by veins) and veinlet terminations (free-ending veins) in leaf tissue under a microscope. Micrometry Automator automates this process using skeletonization and connected component analysis on microscopy images.
- Automated vein islet counting via Zhang-Suen skeletonization + connected component detection
- Veinlet termination counting using endpoint scanning and spatial clustering
- Interactive grid-based region selection with zoomable image viewer
- Physical area filtering (µm²) for accurate islet identification
- Full pipeline: Grid Extraction → CLAHE → Adaptive Threshold → Morphological Closing → Skeletonization → Spur Pruning → Feature Extraction
Screenshot coming soon
What Is CASA (Computer Aided Sperm Analysis)?
Computer Aided Sperm Analysis (CASA) is a technology that uses image processing algorithms to objectively assess sperm motility, morphology, and concentration from microscopy video or image sequences. Micrometry Automator provides CASA capabilities through its advanced particle detection and tracking pipeline, enabling automated semen analysis in reproductive biology and veterinary laboratories.
- Automated sperm detection and counting from microscopy images
- Morphology assessment with size and shape parameter measurements
- Concentration calculation with calibrated field-of-view measurements
- Exportable PDF reports with detailed analysis results and statistics
Screenshot coming soon
How Does Microscopy Calibration Work?
Micrometry Automator includes a guided calibration workflow that uses a stage micrometer to establish the exact microns-per-pixel ratio for each microscope objective. This ensures all measurements — particle sizes, distances, areas — are converted from pixels to real-world micron units with traceable accuracy.
- Interactive guided calibration using captured stage micrometer images
- Save multiple calibration profiles per objective (name, magnification, µm/px, instrument ID)
- Automatic pixel-to-micron conversion across all measurement and analysis tools
- Calibration profile import/export between instruments
Screenshot coming soon
What Image Capture and Management Tools Are Available?
Micrometry Automator connects directly to microscope cameras for live preview and high-resolution image capture. Every captured image is stored with full metadata — sample name, batch number, calibration profile, capturing user, and timestamp — making it easy to search, filter, and review your image library.
- Live camera preview with configurable exposure (auto/manual), gain, resolution, bit depth, and binning
- TIFF image capture with sample name, batch number, and remark metadata
- Searchable, filterable image records with pagination
- Zoomable image viewer with pan support for high-resolution microscopy images
- Line measurements and shape annotations with labels directly on images
Screenshot coming soon
What Security and Compliance Features Are Included?
Micrometry Automator is built with pharmaceutical-grade security from the ground up. It includes AES-256 encrypted database storage, role-based access control, comprehensive audit trailing, PBKDF2-SHA256 password hashing, session management, and compliance with India's DPDP Act 2023. The architecture is designed with 21 CFR Part 11 awareness for regulated GMP/GLP laboratories.
AES-256 Encryption
SQLCipher encrypted database with hardware-derived keys
Role-Based Access
Granular permissions with resource + action pairs per role
Audit Trail
Every user action logged with timestamp, user, and details
Password Security
PBKDF2-SHA256 (100K iterations), 90-day expiry, complexity rules
Account Lockout
5 failed attempts triggers 15-minute lockout
Session Timeout
30-minute inactivity auto-logout for unattended workstations
DPDP Act 2023
Full compliance with India's data protection law
21 CFR Part 11
Architecture designed for FDA electronic records compliance
Encrypted Backups
Manual and automatic backups with integrity verification
What Cameras Are Compatible with Micrometry Automator?
Micrometry Automator provides native integration with Tucsen MIchrome 20 series microscopy cameras for full control over exposure, gain, resolution, bit depth, and binning. It also supports any DirectShow-compatible USB camera as a fallback, making it adaptable to a wide range of laboratory microscope setups.
| Camera Type | SDK | Control Level |
|---|---|---|
| Tucsen MIchrome 20 | Native TUCam SDK | Full (exposure, gain, resolution, bit depth, binning) |
| DirectShow USB cameras | AForge.Video | Standard (resolution, basic settings) |
- Saveable camera settings presets for consistent capture conditions
- Tucsen driver v2.1.6.1 bundled with installer — no separate download needed
Screenshot coming soon
See Micrometry Automator in Action
Contact our sales team for a personalized demo tailored to your laboratory's specific measurement needs.